Format dehidrogenaza (akceptor)
Format dehidrogenaza (akceptor) (EC 1.1.99.33, FDHH, FDH-H, FDH-O, formatna dehidrogenaza H, formatna dehidrogenaza O) je enzim sa sistematskim imenom format:akceptor oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Format dehidrogenaza (akceptor) | |||||||||
---|---|---|---|---|---|---|---|---|---|
Identifikatori | |||||||||
EC broj | 1.1.99.33 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
|
- format + akceptor CO2 + redukovani akceptor
Format dehidrogenaza je citoplazmični enzim koji oksiduje format bez transfera kiseonika.
Reference
uredi- ↑ Axley, M.J., Grahame, D.A. and Stadtman, T.C. (1990). „Escherichia coli formate-hydrogen lyase. Purification and properties of the selenium-dependent formate dehydrogenase component”. J. Biol. Chem. 265: 18213-18218. PMID 2211698.
- ↑ Gladyshev, V.N., Boyington, J.C., Khangulov, S.V., Grahame, D.A., Stadtman, T.C. and Sun, P.D. (1996). „Characterization of crystalline formate dehydrogenase H from Escherichia coli. Stabilization, EPR spectroscopy, and preliminary crystallographic analysis”. J. Biol. Chem. 271: 8095-8100. PMID 8626495.
- ↑ Khangulov, S.V., Gladyshev, V.N., Dismukes, G.C. and Stadtman, T.C. (1998). „Selenium-containing formate dehydrogenase H from Escherichia coli: a molybdopterin enzyme that catalyzes formate oxidation without oxygen transfer”. Biochemistry 37: 3518-3528. PMID 9521673.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.