Flavon sintaza
Flavon sintaza (EC 1.14.11.22, flavonska sintaza) je enzim sa sistematskim imenom flavanon,2-oksoglutarat:kiseonik oksidoreduktaza (dehidracija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Flavon sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.11.22 | ||||||||
| CAS broj | 138263-98-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Za rad ovog enzima se neophodni Fe2+ i askorbat.
Reference uredi
- ↑ Martens, S., Forkmann, G., Matern, U. and Lukačin, R. (2001). „Cloning of parsley flavone synthase I”. Phytochemistry 58: 43-46. PMID 11524111.
- ↑ Lukačin, R., Matern, U., Junghanns, K.T., Heskamp, M.L., Britsch, L., Forkmann, G. and Martens, S. (2001). „Purification and antigenicity of flavone synthase I from irradiated parsley cells”. Arch. Biochem. Biophys. 393: 177-183. PMID 11516175.
- ↑ Martens, S., Forkmann, G., Britsch, L., Wellmann, F., Matern, U. and Lukačin, R. (2003). „Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley”. FEBS Lett. 544: 93-98. PMID 12782296.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.