Fikocijanobilin:feredoksin oksidoreduktaza
Fikocijanobilin:feredoksin oksidoreduktaza (EC 1.3.7.5, oksidoreduktaza fikocijanobilin:feredoksin) je enzim sa sistematskim imenom (3Z)-fikocijanobilin:feredoksin oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Fikocijanobilin:feredoksin oksidoreduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.7.5 | ||||||||
| CAS broj | 347401-12-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (3Z)-fikocijanobilin + oksidovani feredoksin biliverdin IXalfa + redukovani feredoksin
Ovaj enzim katalizuje četvoroelektronsku redukciju biliverdina IX alfa (dvoelektronsku redukciju na oba prstena: A i D). Reakcija teče putem 2-elektronskog intermedijera, 181,182-dihidrobiliverdina. Flavodoksini mogu da koriste feredoksin.
Reference
uredi- ↑ Frankenberg, N., Mukougawa, K., Kohchi, T. and Lagarias, J.C. (2001). „Functional genomic analysis of the HY2 family of ferredoxin-dependent bilin reductases from oxygenic photosynthetic organisms”. Plant Cell 13: 965-978. PMID 11283349.
- ↑ Beale, S.I. (1993). „Biosynthesis of phycobilins”. Chem. Rev. 93: 785-802.
- ↑ Wu, S.-H., McDowell, M.T. and Lagarias, J.C. (1997). „Phycocyanobilin is the natural chromophore precursor of phytochrome from the green alga Mesotaenium caldariorum”. J. Biol. Chem. 272: 25700-25705. PMID 9325294.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.