(3S,6E)-nerolidolna sintaza
(Preusmjereno sa stranice FaNES1)
(3S,6E)-nerolidolna sintaza (EC 4.2.3.48, (E)-nerolidolna sintaza, nerolidolna sintaza, (3S)-(E)-nerolidol sintaza, FaNES1) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (formira (3S,6E)-nerolidol).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| (3S,6E)-nerolidolna sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.48 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnezil difosfat + H2O (3S,6E)-nerolidol + difosfat
Ovaj enzim katalizuje jedan od koraka u formiranju (3E)-4,8-dimetilnona-1,3,7-triena.
Reference uredi
- ↑ Aharoni, A., Giri, A.P., Verstappen, F.W., Bertea, C.M., Sevenier, R., Sun, Z., Jongsma, M.A., Schwab, W. and Bouwmeester, H.J. (2004). „Gain and loss of fruit flavor compounds produced by wild and cultivated strawberry species”. Plant Cell 16: 3110-3131. PMID 15522848.
- ↑ Bouwmeester, H.J., Verstappen, F.W., Posthumus, M.A. and Dicke, M. (1999). „Spider mite-induced (3S)-(E)-nerolidol synthase activity in cucumber and lima bean. The first dedicated step in acyclic C11-homoterpene biosynthesis”. Plant Physiol. 121: 173-180. PMID 10482672.
- ↑ Degenhardt, J. and Gershenzon, J. (2000). „Demonstration and characterization of (E)-nerolidol synthase from maize: a herbivore-inducible terpene synthase participating in (3E)-4,8-dimethyl-1,3,7-nonatriene biosynthesis”. Planta 210: 815-822. PMID 10805454.
- ↑ Arimura, G., Garms, S., Maffei, M., Bossi, S., Schulze, B., Leitner, M., Mithofer, A. and Boland, W. (2008). „Herbivore-induced terpenoid emission in Medicago truncatula: concerted action of jasmonate, ethylene and calcium signaling”. Planta 227: 453-464. PMID 17924138.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.