FMN reduktaza
FMN reduktaza (EC 1.5.1.29, NAD(P)H-FMN reduktaza (nespecifična), NAD(P)H-zavisni FMN reduktaza (nespecifična), NAD(P)H:FMN oksidoreduktaza (nespecifična), NAD(P)H:flavinska oksidoreduktaza (nespecifična), NAD(P)H2 dehidrogenaza (FMN) (nespecifična), NAD(P)H2:FMN oksidoreduktaza (nespecifična), riboflavin mononukleotid reduktaza (nespecifična), flavine mononukleotid reduktaza (nespecifična), riboflavin mononukleotid (redukovani nikotinamid adenin dinukleotid (fosfat)) reduktaza, flavin mononukleotid reduktaza (nespecifična), riboflavin mononukleotid reduktaza (nespecifična), Fre (nespecifična)) je enzim sa sistematskim imenom riboflavin:NAD(P)+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| FMN reduktaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.1.29 | ||||||||
| CAS broj | 64295-83-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- redukovani riboflavin + NAD(P)+ riboflavin + NAD(P)H + H+
Ovaj enzim katalizuje redukciju rastvornih flavina redukcijom piridinskih nukleotida.
Reference
uredi- ↑ Fontecave, M., Eliasson, R. and Reichard, P. (1987). „NAD(P)H:flavin oxidoreductase of Escherichia coli. A ferric iron reductase participating in the generation of the free radical of ribonucleotide reductase”. J. Biol. Chem. 262: 12325-12331. PMID 3305505.
- ↑ Spyrou, G., Haggård-Ljungquist, E., Krook, M., Jörnvall, H., Nilsson, E. and Reichard, P. (1991). „Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme”. J. Bacteriol. 173: 3673-3679. PMID 2050627.
- ↑ Ingelman, M., Ramaswamy, S., Nivière, V., Fontecave, M. and Eklund, H. (1999). „Crystal structure of NAD(P)H:flavin oxidoreductase from Escherichia coli”. Biochemistry 38: 7040-7049. PMID 10353815.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.