Enoil-KoA reduktaza 2-metil-razgranatog lanca
Enoil-KoA reduktaza 2-metil-razgranatog lanca (EC 1.3.8.5, 2-metil razgranati lanac enoil KoA reduktaza) je enzim sa sistematskim imenom 2-metil-razgranati-lanac-acil-KoA:elektron-transfer flavoprotein 2-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Enoil-KoA reduktaza 2-metil-razgranatog lanca | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.8.5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-metilbutanoil-KoA + elektron-transfer flavoprotein (E)-2-metilbut-2-enoil-KoA + redukovani elektron-transfer flavoprotein + H+
Ovaj enzim je flavoprotein (FAD) iz Ascaris suum. Enzim funkcioniše u lancu elektronskog transporta.
Reference uredi
- ↑ Komuniecki, R., Fekete, S. and Thissen-Parra, J. (1985). „Purification and characterization of the 2-methyl branched-chain acyl-CoA dehydrogenase, an enzyme involved in NADH-dependent enoyl-CoA reduction in anaerobic mitochondria of the nematode, Ascaris suum”. J. Biol. Chem. 260: 4770-4777. PMID 3988734.
- ↑ Komuniecki, R., McCrury, J., Thissen, J. and Rubin, N. (1989). „Electron-transfer flavoprotein from anaerobic Ascaris suum mitochondria and its role in NADH-dependent 2-methyl branched-chain enoyl-CoA reduction”. Biochim. Biophys. Acta 975: 127-131. PMID 2736251.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.