Farnezol dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.216)
Farnezol dehidrogenaza (EC 1.1.1.216, NADP+-farnezol dehidrogenaza, farnezol (nikotinamid adenin dinukleotid fosfat) dehidrogenaza) je enzim sa sistematskim imenom (2E,6E)-farnezol:NADP+ 1-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Farnezol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.216 | ||||||||
| CAS broj | 90804-55-0&title= 89089-75-8, 90804-55-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnezol + NADP+ (2E,6E)-farnezal + NADPH + H+
Takođe deluje, mada sporo, na (2Z,6E)-farnezol, geraniol, citronerol i nerol.
Reference uredi
- ↑ Inoue, H., Tsuji, H. and Uritani, I. (1984). „Characterization and activity change of farnesol dehydrogenase in black rot fungus-infected sweet-potato”. Agric. Biol. Chem. 48: 733-738.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.