Glukonat 2-dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.215)
Glukonat 2-dehidrogenaza (EC 1.1.1.215, 2-keto-D-glukonat reduktaza, 2-ketoglukonat reduktaza) je enzim sa sistematskim imenom D-glukonat:NADP+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukonat 2-dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.215 | ||||||||
| CAS broj | 68417-42-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-glukonat + NADP+ 2-dehidro-D-glukonat + NADPH + H+
Takođe deluje na L-idonat, D-galaktonat i D-ksilonat.
Reference uredi
- ↑ Adachi, O., Chiyonobu, T., Shinagawa, E., Matsushita, K. and Ameyama, M. (1978). „Crystalline 2-ketogluconate reductase from Acetobacter ascendens, the second instance of crystalline enzyme in genus Acetobacter”. Agric. Biol. Chem. 42: 2057-2057.
- ↑ Chiyonobu, T., Shinagawa, E., Adachi, O. and Ameyama, M. (1976). „Purification, crystallization and properties of 2-ketogluconate reductase from Acetobacter rancens”. Agric. Biol. Chem. 40: 175-184.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.