Aldoza-6-fosfat reduktaza (NADPH)
(Preusmjereno sa stranice EC 1.1.1.200)
Aldoza-6-fosfat reduktaza (NADPH) (EC 1.1.1.200, aldoza 6-fosfat reduktaza, NADP+-zavisna aldoza 6-fosfat reduktaza, A6PR, aldoza-6-P reduktaza, aldoza-6-fosfat reduktaza, alditol 6-fosfat:NADP+ 1-oksidoreduktaza) je enzim sa sistematskim imenom D-aldoza-6-fosfat:NADP+ 1-oksidoreduktaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aldoza-6-fosfat reduktaza (NADPH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.200 | ||||||||
| CAS broj | 76901-04-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-sorbitol 6-fosfat + NADP+ D-glukoza 6-fosfat + NADPH + H+
U reverznoj reakciji, on takođe deluje na D-galaktozu 6-fosfat, i u manjoj meri na D-manozu 6-fosfat i 2-dezoksi-D-glukozu 6-fosfat.
Reference uredi
- ↑ Negm, F.B. and Loescher, W.H. (1981). „Characterization and partial-purification of aldose-6-phosphate reductase (alditol-6-phosphate-NADP 1-oxidoreductase) from apple leaves”. Plant Physiol. 67: 139-142. PMID 16661614.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.