Geraniol dehidrogenaza
(Preusmjereno sa stranice EC 1.1.1.183)
Geraniol dehidrogenaza (EC 1.1.1.183, geraniolna dehidrogenaza) je enzim sa sistematskim imenom geraniol:NADP+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Geraniol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.183 | ||||||||
| CAS broj | 56802-96-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- geraniol + NADP+ geranial + NADPH + H+
Geraniolna dehidrogenaza takođe deluje manjom brzinom na farnezol, ali ne na nerol. Ovaj enzim formira smešu poznatu kao citral, koja sadrži geranial i neral. Nije poznato da li se neral formira direktno ovim enzimom, ili putem izomerizacije geraniala.
Reference uredi
- ↑ Potty, V.H. and Bruemmer, J.H. (1970). „Oxidation of geraniol by an enzyme system from orange”. Phytochemistry 9: 1001-1007.
- ↑ Sekiwa-Iijima, Y., Aizawa, Y. and Kubota, K. (2001). „Geraniol dehydrogenase activity related to aroma formation in ginger (Zingiber officinale Roscoe)”. J. Agric. Food Chem. 49: 5902-5906. PMID 11743782.
- ↑ Saito, Y., Ito, S., Koltunow, A.M. and Sakai, H. (2011). „Crystallization and preliminary X-ray analysis of geraniol dehydrogenase from Backhousia citriodora (lemon myrtle)”. Acta Crystallogr. Sect. F Struct. Biol. Cryst. Commun. 67: 665-667. PMID 21636906.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.