Glukoza 1-dehidrogenaza (NADP+)
(Preusmjereno sa stranice EC 1.1.1.119)
Glukoza 1-dehidrogenaza (NADP+) (EC 1.1.1.119, nikotinamid adenin dinukleotid fosfat-vezana aldoheksoza dehidrogenaza, NADP+-vezana aldoheksoza dehidrogenaza, NADP+-zavisna glukoza dehidrogenaza) je enzim sa sistematskim imenom D-glukoza:NADP+ 1-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Glukoza 1-dehidrogenaza (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.1.119 | ||||||||
| CAS broj | 37250-50-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-glukoza + NADP+ D-glukono-1,5-lakton + NADPH + H+
Glukozna 1-dehidrogenaza takođe oksiduje D-manozu, 2-dezoksi-D-glukozu i 2-amino-2-dezoksi-D-manozu.
Reference uredi
- ↑ Adachi, O. and Ameyama, M. (1982). „D-Glucose dehydrogenase from Gluconobacter suboxydans”. Methods Enzymol. 89: 159-163.
- ↑ Avigad, G., Alroy, Y. and Englard, S. (1968). „Purification and properties of a nicotinamide adenine dinucleotide phosphate-linked aldohexose dehydrogenase from Gluconobacter cerinus”. J. Biol. Chem. 243: 1936-1941. PMID 4384672.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.