Dibenzotiofen dihidrodiol dehidrogenaza
Dibenzotiofen dihidrodiol dehidrogenaza (EC 1.3.1.60, dibenzotiofen dihidrodiolna dehidrogenaza) je enzim sa sistematskim imenom cis-1,2-dihidroksi-1,2-dihidrodibenzotiofen:NAD+ oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Dibenzotiofen dihidrodiol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.60 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- cis-1,2-dihidroksi-1,2-dihidrodibenzotiofen + NAD+ 1,2-dihidroksidibenzotiofen + NADH + H+
Ovaj enzim učestvuje u degradaciji dibenzotiofena kod bakterija.
Reference uredi
- ↑ Laborde, A.L. and Gibson, D.T. (1977). „Metabolism of dibenzothiophene by a Beijerinckia species”. Appl. Environ. Microbiol. 34: 783-790. PMID 596875.
- ↑ Denome, S.A., Stanley, D.C., Olson, E.S. and Young, K.D. (1993). „Metabolism of dibenzothiophene and naphthalene in Pseudomonas strains: complete DNA sequence of an upper naphthalene catabolic pathway”. J. Bacteriol. 175: 6890-6901. PMID 8226631.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.