Diaminobutiratna dekarboksilaza
Diaminobutiratna dekarboksilaza (EC 4.1.1.86, DABA DC, L-2,4-diaminobutirat dekarboksilaza, L-2,4-diaminobutanoat karboksi-lijaza) je enzim sa sistematskim imenom L-2,4-diaminobutanoat karboksilijaza (formira propan-1,3-diamin).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diaminobutiratna dekarboksilaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.1.1.86 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-2,4-diaminobutanoat propan-1,3-diamin + CO2
Za dejstvo ovog piridoksal-fosfatnog proteina je neophodan divalentni katjon.
Reference uredi
- ↑ Yamamoto, S., Tsuzaki, Y., Tougou, K. and Shinoda, S. (1992). „Purification and characterization of L-2,4-diaminobutyrate decarboxylase from Acinetobacter calcoaceticus”. J. Gen. Microbiol. 138: 1461-1465. PMID 1512577.
- ↑ Ikai, H. and Yamamoto, S. (1994). „Cloning and expression in Escherichia coli of the gene encoding a novel L-2,4-diaminobutyrate decarboxylase of Acinetobacter baumannii”. FEMS Microbiol. Lett. 124: 225-228. PMID 7813892.
- ↑ Ikai, H. and Yamamoto, S. (1997). „Identification and analysis of a gene encoding L-2,4-diaminobutyrate:2-ketoglutarate 4-aminotransferase involved in the 1,3-diaminopropane production pathway in Acinetobacter baumannii”. J. Bacteriol. 179: 5118-5125. PMID 9260954.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.