Dehidroglukonat dehidrogenaza
Dehidroglukonat dehidrogenaza (EC 1.1.99.4, ketoglukonatna dehidrogenaza, alfa-ketoglukonatna dehidrogenaza, 2-keto-D-glukonatna dehidrogenaza, 2-oksoglukonatna dehidrogenaza) je enzim sa sistematskim imenom 2-dehidro-D-glukonat:akceptor 2-oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Dehidroglukonat dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.1.99.4 | ||||||||
| CAS broj | 9028-82-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2-dehidro-D-glukonat + akceptor 2,5-didehidro-D-glukonat + redukovani akceptor
Ovaj enzim je A flavoprotein.
Reference uredi
- ↑ Datta, A.G. and Katznelson, H. (1956). „The oxidation of 2-ketogluconate by a partially purified enzyme from Acetobacter melanogenum”. Arch. Biochem. Biophys. 65: 576-578. PMID 13395514.
- ↑ Shinagawa, E. and Ameyama, M. (1982). „2-Keto-D-gluconate dehydrogenase from Gluconobacter melanogenus, membrane-bound”. Methods Enzymol. 89: 194-198.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.