DTDP-4-amino-4,6-didezoksi-D-glukoza transaminaza
(Preusmjereno sa stranice DTDP-4-amino-4,6-dideoxy-D-glucose:2-oxoglutarate aminotransferase)
DTDP-4-amino-4,6-didezoksi-D-glukoza transaminaza (EC 2.6.1.33, timidin difosfo-4-amino-4,6-didezoksiglukozna aminotransferaza, timidin difosfo-4-amino-6-dezoksiglukozna aminotransferaza, timidin difosfo-4-keto-6-dezoksi-D-glukozna transaminaza, timidin difosfo-4-keto-6-dezoksi-D-glukoza-glutaminska transaminaza, TDP-4-keto-6-dezoksi-D-glukozna transaminaza, VioA, dTDP-4-amino-4,6-didezoksi-D-glukoza:2-oksoglutarat aminotransferaza) je enzim sa sistematskim imenom dTDP-4-amino-4,6-didezoksi-alfa-D-glukoza:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| DTDP-4-amino-4,6-didezoksi-D-glukoza transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.33 | ||||||||
| CAS broj | 9023-19-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- dTDP-4-amino-4,6-didezoksi-alfa-D-glukoza + 2-oksoglutarat dTDP-4-dehidro-6-dezoksi-alfa-D-glukoza + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein.
Reference
uredi- ↑ Matsuhashi, M. and Strominger, J.L. (1966). „Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B”. J. Biol. Chem. 241: 4738-4744. PMID 5332731.
- ↑ Wang, Y., Xu, Y., Perepelov, A.V., Qi, Y., Knirel, Y.A., Wang, L. and Feng, L. (2007). „Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7”. J. Bacteriol. 189: 8626-8635. PMID 17905981.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.