DTDP-4-amino-4,6-didezoksigalaktoza transaminaza
(Preusmjereno sa stranice DTDP-4,6-dideoxy-D-galactose:2-oxoglutarate aminotransferase)
DTDP-4-amino-4,6-didezoksigalaktoza transaminaza (EC 2.6.1.59, timidin difosfoaminodidezoksigalaktoza aminotransferaza, timidin difosfat 4-keto-6-dezoksi-D-glukoza transaminaza, WecE, dTDP-4,6-didezoksi-D-galaktoza:2-oksoglutarat aminotransferaza) je enzim sa sistematskim imenom dTDP-4,6-didezoksi-alfa-D-galaktoza:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| DTDP-4-amino-4,6-didezoksigalaktoza transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.59 | ||||||||
| CAS broj | 72560-97-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- dTDP-4-amino-4,6-didezoksi-alfa-D-galaktoza + 2-oksoglutarat dTDP-4-dehidro-6-dezoksi-alfa-D-galaktoza + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Ohashi, H., Matsuhashi, M. and Matsuhashi, S. (1971). „Thymidine diphosphate 4-acetamido-4,6-dideoxyhexoses. IV. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Pasteurella pseudotuberculosis”. J. Biol. Chem. 246: 2325-2330. PMID 4928644.
- ↑ Hwang, B.Y., Lee, H.J., Yang, Y.H., Joo, H.S. and Kim, B.G. (2004). „Characterization and investigation of substrate specificity of the sugar aminotransferase WecE from E. coli K12”. Chem. Biol. 11: 915-925. PMID 15271350.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.