DTDP-3-amino-3,6-didezoksi-alfa-D-glukopiranoza transaminaza
(Preusmjereno sa stranice DTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose transaminase)
DTDP-3-amino-3,6-didezoksi-alfa-D-glukopiranoza transaminaza (EC 2.6.1.89, TylB, TDP-3-keto-6-dezoksi-D-glukozna 3-aminotransferaza, TDP-3-dehidro-6-dezoksi-D-glukoza 3-aminotransferaza, dTDP-3-keto-6-dezoksi-D-glukozna 3-aminotransferaza, dTDP-3-dehidro-6-dezoksi-D-glukozna 3-aminotransferaza) je enzim sa sistematskim imenom dTDP-3-amino-3,6-didezoksi-alfa-D-glukopiranoza:2-oksoglutarat aminotransferaza.[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| DTDP-3-amino-3,6-didezoksi-alfa-D-glukopiranoza transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.89 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- dTDP-3-amino-3,6-didezoksi-alfa-D-glukopiranoza + 2-oksoglutarat dTDP-3-dehidro-6-dezoksi-alfa-D-glukopiranoza + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein. Reakcija se odvija u reverznom smeru.
Reference
uredi- ↑ Melancon, C.E., 3rd, Hong, L., White, J.A., Liu, Y.N. and Liu, H.W. (2007). „Characterization of TDP-4-keto-6-deoxy-D-glucose-3,4-ketoisomerase from the D-mycaminose biosynthetic pathway of Streptomyces fradiae: in vitro activity and substrate specificity studies”. Biochemistry 46: 577-590. PMID 17209568.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.