NADH dehidrogenaza (ubihinon)
NADH dehidrogenaza (ubihinon) (EC 1.6.5.3, ubihinonska reduktaza, tip 1 dehidrogenaza, kompleks 1 dehidrogenaza, koenzim Q reduktaza, kompleks I (lanac transporta elektrona), kompleks I (mitohondrijalni elektronsk transport), kompleks I (NADH:Q1 oksidoreduktaza), dihidronikotinamid adenin dinukleotid-koenzim Q reduktaza, DPNH-koenzim Q reduktaza, DPNH-ubihinon reduktaza, mitohondrijalni elektronski transportni kompleks 1, mitohondrijalni elektronski transportni kompleks I, NADH koenzim Q1 reduktaza, NADH-koenzim Q oksidoreduktaza, NADH-koenzim Q reduktaza, NADH-CoQ oksidoreduktaza, NADH-CoQ reduktaza, NADH-ubihinonska reduktaza, NADH-ubihinonska oksidoreduktaza, NADH-ubihinon-1 reduktaza, redukovani nikotinamid adenin dinukleotid-koenzim Q reduktaza, NADH:ubihinon oksidoreduktazni kompleks, NADH-Q6 oksidoreduktaza, kompleks transfera elektrona I, NADH2 dehidrogenaza (ubihinon)) je enzim sa sistematskim imenom NADH:ubihinon oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| NADH dehidrogenaza (ubihinon) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 1.6.5.3 | ||||||||
| CAS broj | 9028-04-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Ovaj enzim je flavoprotein koji sadrži gvožđe-sumporne klustere.
Reference uredi
- ↑ Hatefi, Y., Ragan, C.I. and Galante, Y.M. (1985). „The enzymes and the enzyme complexes of the mitochondrial oxidative phosphorylation system”. u: Martonosi, A.. The Enzymes of Biological Membranes. 4 (2nd izd.). New York: Plenum Press. str. 1-70.
- ↑ Herter, S.M., Kortluke, C.M. and Drews, G. (1998). „Complex I of Rhodobacter capsulatus and its role in reverted electron transport”. Arch. Microbiol. 169: 98-105. PMID 9446680.
- ↑ Hunte, C., Zickermann, V. and Brandt, U. (2010). „Functional modules and structural basis of conformational coupling in mitochondrial complex I”. Science 329: 448-451. PMID 20595580.
- ↑ Efremov, R.G., Baradaran, R. and Sazanov, L.A. (2010). „The architecture of respiratory complex I”. Nature 465: 441-445. PMID 20505720.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.