Dihidroksifenilalanin transaminaza
(Preusmjereno sa stranice DOPAATS)
Dihidroksifenilalanin transaminaza (EC 2.6.1.49, dopa transaminaza, dihidroksifenilalaninska aminotransferaza, aspartat-DOPP transaminaza (ADT), L-dopa transaminaza, dopa aminotransferaza, glutamat-DOPP transaminaza (GDT), fenilalanin-DOPP transaminaza (PDT), DOPA 2-oksoglutaratna aminotransferaza, DOPAATS) je enzim sa sistematskim imenom 3,4-dihidroksi-L-fenilalanin:2-oksoglutarat aminotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Dihidroksifenilalanin transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.49 | ||||||||
| CAS broj | 37277-98-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-dopa + 2-oksoglutarat 3,4-dihidroksifenilpiruvat + L-glutamat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Fonnum, F. and Larsen, K. (1965). „Purification and properties of dihydroxyphenylalanine transaminase from guinea pig brain”. J. Neurochem. 12: 589-598. PMID 5829872.
- ↑ Ranjith, N.K., Sasikala, Ch. and Ramana, Ch.V. (2007). „Catabolism of L-phenylalanine and L-tyrosine by Rhodobacter sphaeroides OU5 occurs through 3,4-dihydroxyphenylalanine”. Res. Microbiol. 158: 506-511. PMID 17616348.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.