D-prolin dehidrogenaza
(Preusmjereno sa stranice D-Pro dehydrogenase)
D-prolin dehidrogenaza (EC 1.5.99.13, D-Pro DH, D-Pro dehidrogenaza, D-prolinska dehidrogenaza) je enzim sa sistematskim imenom D-prolin:akceptor oksidoreduktaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| D-prolin dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.5.99.13 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- D-prolin + akceptor 1-pirolidin-2-karboksilat + redukovani akceptor
Ovaj enzim je flavoprotein (FAD). On preferentno deluje na D-prolin, a u manjoj meri i na druge D-aminokiseline.
Reference uredi
- ↑ Tani, Y., Tanaka, K., Yabutani, T., Mishima, Y., Sakuraba, H., Ohshima, T. and Motonaka, J. (2008). „Development of a D-amino acids electrochemical sensor based on immobilization of thermostable D-proline dehydrogenase within agar gel membrane”. Anal. Chim. Acta 619: 215-220. PMID 18558115.
- ↑ Satomura, T., Kawakami, R., Sakuraba, H. and Ohshima, T. (2002). „Dye-linked D-proline dehydrogenase from hyperthermophilic archaeon Pyrobaculum islandicum is a novel FAD-dependent amino acid dehydrogenase”. J. Biol. Chem. 277: 12861-12867. PMID 11823469.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.