N-karbamoil-D-aminokiselinska hidrolaza
(Preusmjereno sa stranice D-N-carbamoylase)
N-karbamoil-D-aminokiselinska hidrolaza (EC 3.5.1.77, D-N-karbamoilaza, N-karbamoilaza) je enzim sa sistematskim imenom N-karbamoil-D-aminokiselina amidohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| N-karbamoil-D-aminokiselinska hidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.77 | ||||||||
| CAS broj | 71768-08-6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- N-karbamoil-D-aminokiselina + H2O D-aminokiselina + NH3 + CO2
Ovaj enzim, zajedno sa EC 3.5.1.87 (N-karbamoil-L-aminokiselinskom hidrolazom), EC 5.1.99.5 (hidantoinskom racemazom) i hidantoinazom, formora deo reakcione kaskade poznate kao hidantoinazni proces.
Reference uredi
- ↑ Ogawa, J., Shimizu, S., Yamada, H. (1993). „N-Carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c; purification and characterization”. Eur. J. Biochem. 212: 685-691. PMID 8462543.
- ↑ Altenbuchner, J., Siemann-Herzberg, M. and Syldatk, C. (2001). „Hydantoinases and related enzymes as biocatalysts for the synthesis of unnatural chiral amino acids”. Curr. Opin. Biotechnol. 12: 559-563. PMID 11849938.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.