Citrat-KoA ligaza
Citrat-KoA ligaza (EC 6.2.1.18, citril-KoA sintetaza, citrat:KoA ligaza, citratna tiokinaza) je enzim sa sistematskim imenom citrat:KoA ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Citrat-KoA ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.2.1.18 | ||||||||
| CAS broj | 856428-87-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim je komponenta enzima EC 2.3.3.8, ATP citratne sintaza.
Reference uredi
- ↑ Lill, U., Schreil, A. and Eggerer, H. (1982). „Isolation of enzymically active fragments formed by limited proteolysis of ATP citrate lyase”. Eur. J. Biochem. 125: 645-650. PMID 6749502.
- ↑ Aoshima, M., Ishii, M. and Igarashi, Y. (2004). „A novel enzyme, citryl-CoA synthetase, catalysing the first step of the citrate cleavage reaction in Hydrogenobacter thermophilus TK-6”. Mol. Microbiol. 52: 751-761. PMID 15101981.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.