Cistationinska b-lijaza
Cistationinska b-lijaza (EC 4.4.1.8, beta-cistationaza, cistinska lijaza, cistationinska L-homocistein-lijaza (deaminacija), L-cistationinska L-homocistein-lijaza (deaminacija)) je enzim sa sistematskim imenom L-cistationin L-homocistein-lijaza (deaminacija, formira piruvat).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Cistationinska b-lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Cistationinska b-lijaza tetramer, E.Coli | |||||||||
| Identifikatori | |||||||||
| EC broj | 4.4.1.8 | ||||||||
| CAS broj | 2613435 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- L-cistationin + H2O L-homocistein + NH3 + piruvat
Ovaj enzim je piridoksal-fosfatni protein.
Reference uredi
- ↑ Anderson, N.W. and Thompson, J.F. (1979). „Cystine lyase: β-cystathionase from turnip roots”. Phytochemistry 18: 1953-1958.
- ↑ Flavin, M. and Slaughter, C. (1964). „Cystathionine cleavage enzymes of Neurospora”. J. Biol. Chem. 239: 2212-2219. PMID 14209950.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.