CDP-paratozna 2-epimeraza
(Preusmjereno sa stranice CDP-tyvelose 2-epimerase,)
CDP-paratozna 2-epimeraza (EC 5.1.3.10, CDP-paratozna epimeraza, citidin difosfoabekvozna epimeraza, citidin difosfodidezoksiglukozna epimeraza, citidin difosfoparatozna epimeraza, citidin difosfatna paratoza-2-epimeraza, CDP-abekvozna epimeraza, CDP-D-abekvozna 2-epimeraza, CDP-tivelozna 2-epimeraza,) je enzim sa sistematskim imenom CDP-3,6-didezoksi-D-glukoza 2-epimeraza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
CDP-paratozna 2-epimeraza | |||||||||
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Identifikatori | |||||||||
EC broj | 5.1.3.10 | ||||||||
CAS broj | 37318-36-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- CDP-3,6-didezoksi-D-glukoza CDP-3,6-didezoksi-D-manoza
Za dejstvo ovog enzima je neophodan NAD+.
Reference uredi
- ↑ Matsuhashi, S. (1966). „Enzymatic synthesis of cytidine diphosphate 3,6-dideoxyhexoses. II. Reversible 2-epimerization of cytidine diphosphate paratose”. J. Biol. Chem. 241: 4275-4282. PMID 5924649.
- ↑ Liu, H.-W. and Thorson, J.S. (1994). „Pathways and mechanisms in the biogenesis of novel deoxysugars by bacteria”. Annu. Rev. Microbiol. 48: 223-256. PMID 7826006.
- ↑ Koropatkin, N.M., Liu, H.W. and Holden, H.M. (2003). „High resolution x-ray structure of tyvelose epimerase from Salmonella typhi”. J. Biol. Chem. 278: 20874-20881. PMID 12642575.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.