CDP-arheol sintaza
CDP-arheol sintaza (EC 2.7.7.67, CDP-2,3-di-O-geranilgeranil-sn-glicerol sintaza, CTP:2,3-GG-GP etar citidililtransferaza, CTP:2,3-di-O-geranilgeranil-sn-glicero-1-fosfat citidiltransferaza) je enzim sa sistematskim imenom CTP:2,3-bis-O-(geranilgeranil)-sn-glicero-1-fosfat citidililtransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| CDP-arheol sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.7.67 | ||||||||
| CAS broj | 329791-09-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- CTP + 2,3-bis-O-(geranilgeranil)-sn-glicero-1-fosfat difosfat + CDP-2,3-bis-O-(geranilgeranil)-sn-glicerol
Ovaj enzim katalizuje jedan od koraka biosinteze polarnih lipida kod arheja.
Reference
uredi- ↑ Morii, H., Nishihara, M. and Koga, Y. (2000). „CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase in the methanogenic archaeon Methanothermobacter thermoautotrophicus”. J. Biol. Chem. 275: 36568-36574. PMID 10960477.
- ↑ Morii, H. and Koga, Y. (2003). „CDP-2,3-di-O-geranylgeranyl-sn-glycerol:L-serine O-archaetidyltransferase (archaetidylserine synthase) in the methanogenic archaeon Methanothermobacter thermautotrophicus”. J. Bacteriol. 185: 1181-1189. PMID 12562787.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.