Biuretna amidohidrolaza
Biuretna amidohidrolaza (EC 3.5.1.84) je enzim sa sistematskim imenom biuret amidohidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Biuretna amidohidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.5.1.84 | ||||||||
| CAS broj | 95567-88-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- biuret + H2O ureja-1-karboksilat + NH3
Ovaj enzim zajedno sa EC 3.5.2.15 (cijanurinsko kiselinskom amidohidrolazom) i EC 3.5.1.54 (alofanatnom hidrolazome) formira deo cijanurinsko-kiselinskog metaboličkog puta.
Reference uredi
- ↑ Cook, A.M., Beilstein, P., Grossenbacher, H. and Hutter, R. (1985). „Ring cleavage and degradative pathway of cyanuric acid in bacteria”. Biochem. J. 231: 25-30. PMID 3904735.
- ↑ Cheng, G., Shapir, N., Sadowsky, M.J. and Wackett, L.P. (2005). „Allophanate hydrolase, not urease, functions in bacterial cyanuric acid metabolism”. Appl. Environ. Microbiol. 71: 4437-4445. PMID 16085834.
- ↑ Shapir, N., Sadowsky, M.J. and Wackett, L.P. (2005). „Purification and characterization of allophanate hydrolase (AtzF) from Pseudomonas sp. strain ADP”. J. Bacteriol. 187: 3731-3738. PMID 15901697.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.