B-lizinska 5,6-aminomutaza
B-lizinska 5,6-aminomutaza (EC 5.4.3.3, beta-lizinska mutaza, L-beta-lizinska 5,6-aminomutaza) je enzim sa sistematskim imenom (3S)-3,6-diaminoheksanoat 5,6-aminomutaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
B-lizinska 5,6-aminomutaza | |||||||||
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Identifikatori | |||||||||
EC broj | 5.4.3.3 | ||||||||
CAS broj | 9075-69-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- (3S)-3,6-diaminoheksanoat (3S,5S)-3,5-diaminoheksanoat
Za dejstvo ovog enzima je neophodan kobamidni koenzim.
Reference
uredi- ↑ Retey, J., Kunz, F., Arigoni, D. and Stadtman, T.C. (1978). „Zur Kenntnis der β-Lysin-Mutase-Reaktion: mechanismus und sterischer Verlauf”. Helv. Chim. Acta 61: 2989-2998.
- ↑ Stadtman, T.C. and Renz, P. (1968). „Anaerobic degradation of lysine. V. Some properties of the cobamide coenzyme-dependent β-lysine mutase of Clostridium sticklandii”. Arch. Biochem. Biophys. 125: 226-239. PMID 5649516.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.