Atrazinska hlorohidrolaza
Atrazinska hlorohidrolaza (EC 3.8.1.8, AtzA) je enzim sa sistematskim imenom atrazin hlorohidrolaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Atrazinska hlorohidrolaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| |||||||||
| Atrazinska hlorohidrolaza hexamer, Pseudomonas sp. adp | |||||||||
| Identifikatori | |||||||||
| EC broj | 3.8.1.8 | ||||||||
| CAS broj | 168680-16-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- atrazin + H2O 4-(etilamino)-2-hidroksi-6-(izopropilamino)-1,3,5-triazin + hlorid
Ovaj enzim učestvuje u degradaciji herbicida atrazina, 2-hloro-4-(etilamino)-6-(izopropilamino)-1,3,5-triazina, u bakterijama.
Reference uredi
- ↑ de Souza, M.L., Wackett, L.P., Boundy-Mills, K.L., Mandelbaum, R.T. and Sadowsky, M.J. (1995). „Cloning, characterization, and expression of a gene region from Pseudomonas sp. strain ADP involved in the dechlorination of atrazine”. Appl. Environ. Microbiol. 61: 3373-3378. PMID 7574646.
- ↑ de Souza, M.L., Sadowsky, M.J. and Wackett, L.P. (1996). „Atrazine chlorohydrolase from Pseudomonas sp. strain ADP: gene sequence, enzyme purification, and protein characterization”. J. Bacteriol. 178: 4894-4900. PMID 8759853.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.