Aminopeptidaza Ei
Aminopeptidaza Ei (EC 3.4.11.20, Aminopeptidase Ey) je enzim.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aminopeptidaza Ei | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.4.11.20 | ||||||||
| CAS broj | 9031-94-1 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- Ovi enzimi za razliku od drugih aminopeptidaza imaju široku specifičnost za aminokiseline u P1 poziciji i sposobnost da hidrolizuju peptide sa četiri ili pet ostataka koji sadrže Pro u P1' poziciji
Ovaj cinkov glikoprotein iz peptidazne familije M1 (membranska alanil aminopeptidazna familija), se sastoji od dve 150 kDa podjedinice.
Reference
uredi- ↑ Ichishima, E., Yamagata, Y., Chiba, H., Sawaguchi, K. and Tanaka, T. (1989). „Soluble and bound forms of aminopeptidase in hens egg-yolk”. Agric. Biol. Chem. 53: 1867-1872.
- ↑ Tanaka, T. and Ichishima, E. (1993). „Substrate specificity of aminopeptidase Ey from hen's egg yolk”. Comp. Biochem. Physiol. [B] 105: 105-110. PMID 7684960.
- ↑ Tanaka, T. and Ichishima, E. (1993). „Molecular properties of aminopeptidase Ey as a zinc-metalloenzyme”. Int. J. Biochem. 25: 1681-1688. PMID 8288037.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.