Alfa-kopaenska sintaza
Alfa-kopaenska sintaza (EC 4.2.3.133, Alpha-copaene synthase) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat difosfat-lijaza (ciklizacija, formira alfa-kopaen).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alfa-kopaenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.133 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnezil difosfat (-)-alfa-kopaen + difosfat
Ovaj enzim je izolovan iz Helianthus annuus (suncokreta).
Reference uredi
- ↑ Gopfert, J.C., Macnevin, G., Ro, D.K. and Spring, O. (2009). „Identification, functional characterization and developmental regulation of sesquiterpene synthases from sunflower capitate glandular trichomes”. BMC Plant Biol. 9: #86-86. PMID 19580670.
- ↑ Xie, X., Kirby, J. and Keasling, J.D. (2012). „Functional characterization of four sesquiterpene synthases from Ricinus communis (castor bean)”. Phytochemistry 78: 20-28. PMID 22459969.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.