Alfa-farnezenska sintaza
Alfa-farnezenska sintaza (EC 4.2.3.46, (E,E)-alfa-farnezen sintaza, AFS1, MdAFS1) je enzim sa sistematskim imenom (2E,6E)-farnezil-difosfat lijaza (formira (3E,6E)-alfa-farnezen).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alfa-farnezenska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.3.46 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (2E,6E)-farnezil difosfat (3E,6E)-alfa-farnezen + difosfat
Reference
uredi- ↑ Pechous, S.W. and Whitaker, B.D. (2004). „Cloning and functional expression of an (E,E)-α-farnesene synthase cDNA from peel tissue of apple fruit”. Planta 219: 84-94. PMID 14740213.
- ↑ Green, S., Squire, C.J., Nieuwenhuizen, N.J., Baker, E.N. and Laing, W. (2009). „Defining the potassium binding region in an apple terpene synthase”. J. Biol. Chem. 284: 8661-8669. PMID 19181671.
- ↑ Nieuwenhuizen, N.J., Wang, M.Y., Matich, A.J., Green, S.A., Chen, X., Yauk, Y.K., Beuning, L.L., Nagegowda, D.A., Dudareva, N. and Atkinson, R.G. (2009). „Two terpene synthases are responsible for the major sesquiterpenes emitted from the flowers of kiwifruit (Actinidia deliciosa)”. J. Exp. Bot. 60: 3203-3219. PMID 19516075.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.