Aldehid reduktaza
Aldehid reduktaza (EC 1.1.1.21, aldehidna reduktaza, aldoza reduktaza, poliol dehidrogenaza (NADP+), ALR2, alditol:NADP+ oksidoreduktaza, alditol:NADP+ 1-oksidoreduktaza, NADPH-aldopentoza reduktaza, NADPH-aldoza reduktaza) je enzim sa sistematskim imenom alditol:NAD(P)+ 1-oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Aldehid reduktaza | |||||||||
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| Identifikatori | |||||||||
| EC broj | 1.1.1.21 | ||||||||
| CAS broj | 9028-31-3 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- alditol + NAD(P)+ aldoza + NAD(P)H + H+
Ima široku specifičnost.
Reference uredi
- ↑ Attwood, M.A. and Doughty, C.C. (1974). „Purification and properties of calf liver aldose reductase”. Biochim. Biophys. Acta 370: 358-368. PMID 4216364.
- ↑ Boghosian, R.A. and McGuinness, E.T. (1979). „Affinity purification and properties of porcine brain aldose reductase”. Biochim. Biophys. Acta 567: 278-286. PMID 36151.
- ↑ Hers, H.G. (1960). „L’Aldose-réductase”. Biochim. Biophys. Acta 37: 120-126. PMID 14401390.
- ↑ Scher, B.M. and Horecker, B.L. (1966). „Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis”. Arch. Biochem. Biophys. 116: 117-128. PMID 4381350.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.
- Denise R., PhD. Ferrier (2005). Lippincott's Illustrated Reviews: Biochemistry (Lippincott's Illustrated Reviews). Hagerstown, Maryland: Lippincott Williams & Wilkins. str. 319. ISBN 0-7817-2265-9.