Alantoikaza
Alantoikaza (EC 3.5.3.4) je enzim sa sistematskim imenom alantoat amidinohidrolaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Alantoikaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Identifikatori | |||||||||
| EC broj | 3.5.3.4 | ||||||||
| CAS broj | 9025-21-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- alantoat + H2O (S)-ureidoglikolat + ureja
Ovaj enzim takođe hidrolizuje (R)-ureidoglikolat do glioksilata i ureje.
Reference uredi
- ↑ Florkin, M. and Duchateau-Bosson, G. (1940). „Microdosage photométrique de l’allantoïne en solutions pures et dans l’urine”. Enzymologia 9: 5-9.
- ↑ Trijbels, F. and Vogels, G.D. (1966). „Allantoicase and ureidoglycolase in Pseudomonas and Penicillium species”. Biochim. Biophys. Acta 118: 387-395. PMID 4960174.
- ↑ van der Drift, C. and Vogels, G.D. (1971). „Effect of metal and hydrogen ions on the activity and stability of allantoicase”. Biochim. Biophys. Acta 198: 339-352.
- ↑ 's-Gravenmade, E.J., Vogels, G.D. and Van der Drift, C. (1970). „Hydrolysis, racemization and absolute configuration of ureidoglycolate, a substrate of allantoicase”. Biochim. Biophys. Acta 198: 569-582. PMID 4314237.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.