Adenozilmetionin—8-amino-7-oksononanoat transaminaza
Adenozilmetionin—8-amino-7-oksononanoat transaminaza (EC 2.6.1.62, 7,8-diaminonanoat transaminaza, 7,8-diaminononanoat transaminaza, DAPA transaminaza, 7,8-diaminopelargonska kiselina aminotransferaza, DAPA aminotransferaza, 7-keto-8-aminopelargonska kiselina sintaza, diaminopelargonatna sintaza, 7-keto-8-aminopelargonska kiselina aminotransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:8-amino-7-oksononanoat aminotransferaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Adenozilmetionin—8-amino-7-oksononanoat transaminaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.6.1.62 | ||||||||
| CAS broj | 37259-71-5 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- S-adenozil-L-metionin + 8-amino-7-oksononanoat S-adenozil-4-metiltio-2-oksobutanoat + 7,8-diaminononanoat
S-adenozilhomocistein takođe može da deluje kao donor.
Reference
uredi- ↑ Izumi, Y., Sato, K., Tani, Y. and Ogata, K. (1973). „Purification of 7-keto-8-aminopelargonic acid-7,8-diaminopelargonic acid aminotransferase, an enzyme involved in biotin synthesis, from Brevibacterium divaricatum”. Agric. Biol. Chem. 37: 2683-2684.
- ↑ Izumi, Y., Sato, K., Tani, Y. and Ogata, K. (1975). „7,8-Diaminopelargonic acid aminotransferase, an enzyme involved in biotin synthesis by microorganisms”. Agric. Biol. Chem. 39: 175-181.
- ↑ Stoner, G.L. and Eisenberg, M.A. (1973). „Purification and properties of 7,8-diaminopelargonic acid aminotransferase. An enzyme in the biotin biosynthetic pathway”. J. Biol. Chem. 250: 4029-4036. PMID 1092681.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.