Adenilosukcinatna sintaza
(Preusmjereno sa stranice Adenilosukcinat sintaza)
Adenilosukcinatna sintaza (EC 6.3.4.4, IMP—aspartat ligaza, adenilosukcinat sintetaza, sukcinoadenilna kinosintetaza, sukcino-AMP sintetaza) je enzim sa sistematskim imenom IMP:L-aspartat ligaza (formira GDP).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
Adenilosukcinatna sintaza | |||||||||
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Identifikatori | |||||||||
EC broj | 6.3.4.4 | ||||||||
CAS broj | 9023-57-8 | ||||||||
IntEnz | IntEnz view | ||||||||
BRENDA | BRENDA entry | ||||||||
ExPASy | NiceZyme view | ||||||||
KEGG | KEGG entry | ||||||||
MetaCyc | metabolic pathway | ||||||||
PRIAM | profile | ||||||||
PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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Reference
uredi- ↑ Davey, C.L. (1959). „Synthesis of adenylosuccinic acid in preparations of mammalian skeletal muscle”. Nature 183: 995-996. PMID 13644270.
- ↑ Lieberman, I. (1956). „Enzymatic synthesis of adenosine-5′-phosphate from inosine-5′-phosphate”. J. Biol. Chem. 223: 327-339. PMID 13376602.
- ↑ Yefimochkina, E.F. and Braunstein, A.E. (1959). „The amination of inosinic acid to adenylic acid in muscle extracts”. Arch. Biochem. Biophys. 83: 350-352. PMID 13662023.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.