Acilglicerol kinaza
Acilglicerol kinaza (EC 2.7.1.94, monoacilglicerolna kinaza, monoacilglicerolna kinaza (fosforilacija), sn-2-monoacilglicerolna kinaza, MGK, monogliceridna kinaza, monogliceridna fosfokinaza) je enzim sa sistematskim imenom ATP:acilglicerol 3-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Acilglicerol kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.94 | ||||||||
| CAS broj | 62213-37-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- ATP + acilglicerol ADP + acil-sn-glicerol 3-fosfat
Ovaj enzim deluje na 1- i 2-acilglicerole.
Reference uredi
- ↑ Pieringer, R.A. and Hokin, L.E. (1962). „Biosynthesis of lysophosphatidic acid from monoglyceride and adenosine triphosphate”. J. Biol. Chem. 237: 653-658. PMID 14486486.
- ↑ Pieringer, R.A. and Kunnes, R.S. (1965). „The biosynthesis of phosphatidic acid and lysophosphatidic acid by glyceride phosphokinase pathways in Escherichia coli”. J. Biol. Chem. 240: 2833-2838. PMID 14342303.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.