AMP—timidin kinaza
(Preusmjereno sa stranice AMP:timidin 5'-fosfotransferaza)
AMP—timidin kinaza (EC 2.7.1.114, adenilat-nukleozidna fosfotransferaza) je enzim sa sistematskim imenom AMP:timidin 5'-fosfotransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| AMP—timidin kinaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.7.1.114 | ||||||||
| CAS broj | 60440-28-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Dezoksipirimidinski kinazni kompleks indukovan virusom Herpes simplex katalizuje ovu reakciju, kao i reacije enzima EC 2.7.1.21 (timidin kinaza), EC 2.7.1.118 (ADP---timidin kinaza) i EC 2.7.4.9 (dTMP kinaza).
Reference
uredi- ↑ Falke, D., Labenz, J., Brauer, D. and Muller, W.E.G. (1982). „Adenosine diphosphate: thymidine 5′-phosphotransferase, a new enzyme activity, associated with the Herpes simplex virus-induced deoxypyrimidine kinase”. Biochim. Biophys. Acta 708: 99-103. PMID 6293576.
- ↑ Falke, D., Nehrbass, W., Brauer, D. and Mueller, W.E.G. (1981). „Adenylic acid: deoxythymidine 5′-phosphotransferase: evidence for the existence of a novel Herpes simplex virus-induced enzyme”. J. Gen. Virol. 53: 247-255. PMID 6267178.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.