Adenilil-sulfat reduktaza (tioredoksin)
(Preusmjereno sa stranice AMP,sulfite:thioredoxin-disulfide oxidoreductase (adenosine-5'-phosphosulfate-forming))
Adenilil-sulfat reduktaza (tioredoksin) (EC 1.8.4.10, tioredoksin-zavisna 5'-adenililsulfatna reduktaza) je enzim sa sistematskim imenom AMP,sulfit:tioredoksin-disulfid oksidoreduktaza (formira adenozin-5'-fosfosulfat).[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| Adenilil-sulfat reduktaza (tioredoksin) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.8.4.10 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- AMP + sulfit + tioredoksin disulfid 5'-adenilil sulfat + tioredoksin
Ovaj enzim koristi adenilil sulfat.
Reference uredi
- ↑ Bick, J.A., Dennis, J.J., Zylstra, G.J., Nowack, J. and Leustek, T. (2000). „Identification of a new class of 5-adenylylsulfate (APS) reductase from sulfate-assimilating bacteria”. J. Bacteriol. 182: 135-142. PMID 10613872.
- ↑ Abola, A.P., Willits, M.G., Wang, R.C. and Long, S.R. (1999). „Reduction of adenosine-5′-phosphosulfate instead of 3′-phosphoadenosine-5′-phosphosulfate in cysteine biosynthesis by Rhizobium meliloti and other members of the family Rhizobiaceae”. J. Bacteriol. 181: 5280-5287. PMID 10464198.
- ↑ Williams, S.J., Senaratne, R.H., Mougous, J.D., Riley, L.W. and Bertozzi, C.R. (2002). „5′-Adenosinephosphosulfate lies at a metabolic branchpoint in mycobacteria”. J. Biol. Chem. 277: 32606-32615. PMID 12072441.
- ↑ Neumann, S., Wynen, A., Trüper, H.G. and Dahl, C. (2000). „Characterization of the cys gene locus from Allochromatium vinosum indicates an unusual sulfate assimilation pathway”. Mol. Biol. Rep. 27: 27-33. PMID 10939523.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.