A-aminokiselinska estaraza
A-aminokiselinska estaraza (EC 3.1.1.43, hidrolaza alfa-aminokiselinskog estra) je enzim sa sistematskim imenom alfa-amino-kiselina-estar aminoacilhidrolaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| A-aminokiselinska estaraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 3.1.1.43 | ||||||||
| CAS broj | 74506-40-4 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
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- alfa-aminokiselinski estar + H2O alfa-aminokiselina + alkohol
Ovaj enzim takođe katalizuje alfa-aminoacilni transfer na brojne amino nukleofile.
Reference uredi
- ↑ Kato, K., Kawahara, K., Takahashi, T. and Kakinuma, A. (1980). „Purification of an α-amino acid ester hydrolase from Xanthomonas citri”. Agric. Biol. Chem. 44: 1069-1074.
- ↑ Kato, K., Kawahara, K., Takahashi, T. and Kakinuma, A. (1980). „Substrate specificity of an α-amino acid ester hydrolase from Xanthomonas citri”. Agric. Biol. Chem. 44: 1075-1081.
- ↑ Takahashi, T., Yamazaki, Y. and Kato, K. (1974). „Substrate specificity of an α-amino acid ester hydrolase produced by Acetobacter turbidans A”. T.C.C. 9325. Biochem. J. 137: 497-503. PMID 4424889.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.