9,9'-Dicis-zeta-karoten desaturaza
9,9'-Dicis-zeta-karoten desaturaza (EC 1.3.5.6, zeta-karotenska desaturaza, ZDS) je enzim sa sistematskim imenom 9,9'-dicis-zeta-koroten:hinon oksidoreduktaza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 9,9'-Dicis-zeta-karoten desaturaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.5.6 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 9,9'-dicis-zeta-karoten + 2 hinon 7,9,7',9'-tetracis-likopen + 2 hinol (sveukupna reakcija)
- (1a) 9,9'-dicis-zeta-karoten + hinon 7,9,9'-tricis-neurosporen + hinol
- (1b) 7,9,9'-tricis-neurosporen + hinon 7,9,7',9'-tetracis-likopen + hinol
Ovaj enzim učestvuje u biosintezi karotenoida kod biljki i cijanobakterija.
Reference uredi
- ↑ Albrecht, M., Linden, H. and Sandmann, G. (1996). „Biochemical characterization of purified ζ-carotene desaturase from Anabaena PCC 7120 after expression in E. coli”. Eur. J. Biochem. 236: 115-120. PMID 8617254.
- ↑ Josse, E.M., Simkin, A.J., Gaffe, J., Laboure, A.M., Kuntz, M. and Carol, P. (2000). „A plastid terminal oxidase associated with carotenoid desaturation during chromoplast differentiation”. Plant Physiol. 123: 1427-1436. PMID 10938359.
- ↑ Breitenbach, J., Kuntz, M., Takaichi, S. and Sandmann, G. (1999). „Catalytic properties of an expressed and purified higher plant type ζ-carotene desaturase from Capsicum annuum”. Eur. J. Biochem. 265: 376-383. PMID 10491195.
- ↑ Breitenbach, J. and Sandmann, G. (2005). „ζ-Carotene cis isomers as products and substrates in the plant poly-cis carotenoid biosynthetic pathway to lycopene”. Planta 220: 785-793. PMID 15503129.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.