7-Cijano-7-deazaguaninska sintaza
(Preusmjereno sa stranice 7-carboxy-7-carbaguanine:ammonia ligase (ADP-forming))
7-Cijano-7-deazaguaninska sintaza (EC 6.3.4.20, preQ0 sintaza, 7-cijano-7-karbaguanin sintaza, queC (gen)) je enzim sa sistematskim imenom 7-karboksi-7-karbaguanin:amonijak ligaza (formira ADP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 7-Cijano-7-deazaguaninska sintaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.3.4.20 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Ovaj enzim vezuje Zn2+.
Reference uredi
- ↑ McCarty, R.M., Somogyi, A., Lin, G., Jacobsen, N.E. and Bandarian, V. (2009). „The deazapurine biosynthetic pathway revealed: in vitro enzymatic synthesis of preQ0 from guanosine 5′-triphosphate in four steps”. Biochemistry 48: 3847-3852. PMID 19354300.
- ↑ Cicmil, N. and Huang, R.H. (2008). „Crystal structure of QueC from Bacillus subtilis: an enzyme involved in preQ1 biosynthesis”. Proteins 72: 1084-1088. PMID 18491386.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.