6-karboksiheksanoat-KoA ligaza
6-karboksiheksanoat-KoA ligaza (EC 6.2.1.14, 6-karboksiheksanoil-KoA sintetaza, pimelil-KoA sintetaza) je enzim sa sistematskim imenom 6-karboksiheksanoat:KoA ligaza (formira AMP).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 6-karboksiheksanoat-KoA ligaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 6.2.1.14 | ||||||||
| CAS broj | 55467-50-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
Reference
uredi- ↑ Izumi, Y., Morita, H., Sato, K., Tani, Y. and Ogata, K. (1972). „Synthesis of biotin-vitamers from pimelic acid and coenzyme A by cell-free extracts of various bacteria”. Biochim. Biophys. Acta 264: 210-213. PMID 4623286.
- ↑ Izumi, Y., Morita, H., Tani, Y. and Ogata, K. (1974). „The pimelyl-CoA synthetase responsible for the first step in biotin biosynthesis by microorganisms”. Agric. Biol. Chem. 38: 2257-2262.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.