5-Dehidro-4-dezoksiglukaratna dehidrataza
5-Dehidro-4-dezoksiglukaratna dehidrataza (EC 4.2.1.41, 5-keto-4-dezoksi-glukarat dehidrataza, 5-keto-4-dezoksi-glukarat dehidrataza, dezoksiketoglukaratna dehidrataza, D-4-dezoksi-5-ketoglukarat hidrolijaza, 5-dehidro-4-dezoksi-D-glukarat hidrolijaza (dekarboksilacija)) je enzim sa sistematskim imenom 5-dehidro-4-dezoksi-D-glukarat hidrolijaza (formira dekarboksilacija; 2,5-dioksopentanoat).[1] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 5-Dehidro-4-dezoksiglukaratna dehidrataza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.2.1.41 | ||||||||
| CAS broj | 37290-77-0 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 5-dehidro-4-dezoksi-D-glukarat 2,5-dioksopentanoat + H2O + CO2
Reference
uredi- ↑ Jeffcoat, R., Hassall, H. and Dagley, S. (1969). „Purification and properties of D-4-deoxy-5-oxoglucarate hydro-lyase (decarboxylating)”. Biochem. J. 115: 977-983. PMID 4982840.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.