4-Deoksi-L-treo-5-heksosuloza-uronatna ketol-izomeraza
4-Deoksi-L-treo-5-heksosuloza-uronatna ketol-izomeraza (EC 5.3.1.17, 4-dezoksi-L-treo-5-heksuloza uronat izomeraza, 4-dezoksi-L-treo-5-heksosuloza-uronat ketol-izomeraza, kduI (gen)) je enzim sa sistematskim imenom 5-dehidro-4-dezoksi-D-glukuronat aldoza-ketoza-izomeraza.[1][2][3][4] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 4-Deoksi-L-treo-5-heksosuloza-uronatna ketol-izomeraza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 5.3.1.17 | ||||||||
| CAS broj | 37318-44-8 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 5-dehidro-4-dezoksi-D-glukuronat 3-dezoksi-D-glicero-2,5-heksodiulosonat
Ovaj enzim učestvuje u degradaciji poligalakturonata.
Reference
uredi- ↑ Preiss, J. (1966). „4-Deoxy-L-threo-5-hexosulose uronic acid isomerase”. Methods Enzymol. 9: 602-604.
- ↑ Condemine, G. and Robert-Baudouy, J. (1991). „Analysis of an Erwinia chrysanthemi gene cluster involved in pectin degradation”. Mol. Microbiol. 5: 2191-2202. PMID 1766386.
- ↑ Dunten, P., Jaffe, H. and Aksamit, R.R. (1998). „Crystallization of 5-keto-4-deoxyuronate isomerase from Escherichia coli”. Acta Crystallogr. D Biol. Crystallogr. 54: 678-680. PMID 9761873.
- ↑ Crowther, R.L. and Georgiadis, M.M. (2005). „The crystal structure of 5-keto-4-deoxyuronate isomerase from Escherichia coli”. Proteins 61: 680-684. PMID 16152643.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.