Diapolikopen oksigenaza
(Preusmjereno sa stranice 4,4'-diapolikopen,AH2:kiseonik oksidoreduktaza (4,4'-hidroksilacija))
Diapolikopen oksigenaza (EC 1.14.99.44, CRTP) je enzim sa sistematskim imenom 4,4'-diapolikopen,AH2:kiseonik oksidoreduktaza (4,4'-hidroksilacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Diapolikopen oksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.14.99.44 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 4,4'-diapolikopen + 4 AH2 + 4 O2 4,4'-diapolikopendial + 4 A + 6H2O
Ovaj enzim učestvuje u biosintezi C30 karotenoida, kao što je stafiloksantin.
Reference uredi
- ↑ Mijts, B.N., Lee, P.C. and Schmidt-Dannert, C. (2005). „Identification of a carotenoid oxygenase synthesizing acyclic xanthophylls: combinatorial biosynthesis and directed evolution”. Chem. Biol. 12: 453-460. PMID 15850982.
- ↑ Tao, L., Schenzle, A., Odom, J.M. and Cheng, Q. (2005). „Novel carotenoid oxidase involved in biosynthesis of 4,4′-diapolycopene dialdehyde”. Appl. Environ. Microbiol. 71: 3294-3301. PMID 15933032.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.