3-karboksietilkatehol 2,3-dioksigenaza
3-karboksietilkatehol 2,3-dioksigenaza (EC 1.13.11.16, 2,3-dihidroksi-beta-fenilpropionska dioksigenaza, 2,3-dihidroksi-beta-fenilpropionatna oksigenaza, 3-(2,3-dihidroksifenil)propanoat:kiseonik 1,2-oksidoreduktaza) je enzim sa sistematskim imenom 3-(2,3-dihidroksifenil)propanoat:kiseonik 1,2-oksidoreduktaza (deciklizacija).[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 3-karboksietilkatehol 2,3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.16 | ||||||||
| CAS broj | 105503-63-7 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- (1) 3-(2,3-dihidroksifenil)propanoat + O2 (2Z,4E)-2-hidroksi-6-oksonona-2,4-dien-1,9-dioat
- (2) (2E)-3-(2,3-dihidroksifenil)prop-2-enoat + O2 (2Z,4E,7E)-2-hidroksi-6-oksonona-2,4,7-trien-1,9-dioat
Ovaj protein sadrži gvožđe. Ovaj enzim katalizuje jedan korak u putu degradacije fenilpropanoidnih jedinjenja.
Reference uredi
- ↑ Dagley, S., Chapman, P.J. and Gibson, D.T. (1965). „The metabolism of β-phenylpropionic acid by an Achromobacter”. Biochem. J. 97: 643-650. PMID 5881653.
- ↑ Lam, W. W. Y and Bugg, T. D. H. (1994). „Chemistry of extradiol aromatic ring cleavage: isolation of a stable dienol ring fission intermediate and stereochemistry of its enzymatic hydrolytic clevage”. J. Chem. Soc., Chem. Commun. 10: 1163-1164.
- ↑ Díaz, E., Ferrández, A. and García, J.L. (1998). „Characterization of the hca cluster encoding the dioxygenolytic pathway for initial catabolism of 3-phenylpropionic acid in Escherichia coli K-12”. J. Bacteriol. 180: 2915-2923. PMID 9603882.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.