3-Aminobutiril-KoA amonijak-lijaza
3-Aminobutiril-KoA amonijak-lijaza (EC 4.3.1.14, L-3-aminobutiril-KoA deaminaza, L-3-aminobutiril-KoA amonijak-lijaza) je enzim sa sistematskim imenom L-3-aminobutiril-KoA amonijak-lijaza (formira krotonoil-KoA).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 3-Aminobutiril-KoA amonijak-lijaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 4.3.1.14 | ||||||||
| CAS broj | 55467-41-9 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- L-3-aminobutiril-KoA krotonoil-KoA + NH3
Hidroksilamin može da zameni amonijak kao supstrat.
Reference
uredi- ↑ Jeng, I.-M., Barker, H.A. (1974). „Purification and properties of L-3-aminobutyryl coenzyme A deaminase from a lysine-fermenting Clostridium”. J. Biol. Chem. 249: 6578-6584. PMID 4420467.
- ↑ Barker, H.A., Kahn, J.M., Chew, S. (1980). „Enzymes involved in 3,5-diaminohexanoate degradation by Brevibacterium sp”. J. Bacteriol. 143: 1165-1170. PMID 7410315.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.