2,3-dihidroksibenzoat 2,3-dioksigenaza
2,3-dihidroksibenzoat 2,3-dioksigenaza (EC 1.13.11.28, 2,3-dihidroksibenzoatna 2,3-oksigenaza) je enzim sa sistematskim imenom 2,3-dihidroksibenzoat:kiseonik 2,3-oksidoreduktaza (deciklizacija).[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju:
| 2,3-dihidroksibenzoat 2,3-dioksigenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.13.11.28 | ||||||||
| CAS broj | 56802-97-2 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- 2,3-dihidroksibenzoat + O2 2-karboksi-cis,cis-mukonat
Ovaj enzim takođe deluje, mada sporo, na 2,3-dihidroksi-4-metilbenzoat i 2,3-dihidroksi-4-izopropilbenzoat.
Reference uredi
- ↑ La Du, B.N. and Zannoni, V.G. (1956). „The tyrosine oxidation system of liver. III. Further studies on the oxidation of p-hydroxyphenylpyruvic acid”. J. Biol. Chem. 219: 273-281. PMID 13295279.
- ↑ Sharma, H.K. and Vaidyanathan, C.S. (1975). „A new mode of ring cleavage of 2,3-dihydroxybenzoic acid in Tecoma stans (L.). Partial purification and properties of 2,3-dihydroxybenzoate 2,3-oxygenase”. Eur. J. Biochem. 56: 163-171. PMID 1175620.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.