Cis-2,3-dihidrobifenil-2,3-diol dehidrogenaza
(Preusmjereno sa stranice 2,3-dihidro-2,3-dihidroksibifenilna dehidrogenaza)
Cis-2,3-dihidrobifenil-2,3-diol dehidrogenaza (EC 1.3.1.56, 2,3-dihidro-2,3-dihidroksibifenilna dehidrogenaza) je enzim sa sistematskim imenom cis-3-fenilcikloheksa-3,5-dien-1,2-diol:NAD+ oksidoreduktaza.[1][2][3] Ovaj enzim katalizuje sledeću hemijsku reakciju
| Cis-2,3-dihidrobifenil-2,3-diol dehidrogenaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 1.3.1.56 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- cis-3-fenilcikloheksa-3,5-dien-1,2-diol + NAD+ bifenil-2,3-diol + NADH + H+
Ovaj enzim katalizuje drugi korak u degradaciji bifenila kod bakterija.
Reference uredi
- ↑ Sylvestre, M., Hurtubise, Y., Barriault, D., Bergeron, J. and Ahmad, D. (1996). „Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB)”. Appl. Environ. Microbiol. 62: 2710-2715. PMID 8702262.
- ↑ Fukuda, M., Yasukochi, Y., Kikuchi, Y., Nagata, Y., Kimbara, K., Horiuchi, H., Takagi, M. and Yano, K. (1994). „Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls”. Biochem. Biophys. Res. Commun. 202: 850-856. PMID 8048958.
- ↑ Hofer, B., Eltis, L.D., Dowling, D.N. and Timmis, K.N. (1993). „Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation”. Gene 130: 47-55. PMID 8344527.
Literatura uredi
- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.