16S rRNK (uracil1498-N3)-metiltransferaza
16S rRNK (uracil1498-N3)-metiltransferaza (EC 2.1.1.193, DUF558 protein, YggJ, RsmE, m3U1498 specifična metiltransferaza) je enzim sa sistematskim imenom S-adenozil-L-metionin:16S rRNK (uracil1498-N3)-metiltransferaza.[1][2] Ovaj enzim katalizuje sledeću hemijsku reakciju
| 16S rRNK (uracil1498-N3)-metiltransferaza | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifikatori | |||||||||
| EC broj | 2.1.1.193 | ||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB | RCSB PDB PDBe PDBj PDBsum | ||||||||
| |||||||||
- S-adenozil-L-metionin + uracil1498 u 16S rRNK S-adenozil-L-homocistein + N3-metiluracil1498 u 16S rRNK
Ovaj enzim specifično metiliše uracil1498 u N3 poziciji 16S rRNK.
Reference
uredi- ↑ Basturea, G.N., Rudd, K.E. and Deutscher, M.P. (2006). „Identification and characterization of RsmE, the founding member of a new RNA base methyltransferase family”. RNA 12: 426-434. PMID 16431987.
- ↑ Basturea, G.N. and Deutscher, M.P. (2007). „Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE”. RNA 13: 1969-1976. PMID 17872509.
Literatura
uredi- Nicholas C. Price, Lewis Stevens (1999). Fundamentals of Enzymology: The Cell and Molecular Biology of Catalytic Proteins (Third izd.). USA: Oxford University Press. ISBN 019850229X.
- Eric J. Toone (2006). Advances in Enzymology and Related Areas of Molecular Biology, Protein Evolution (Volume 75 izd.). Wiley-Interscience. ISBN 0471205036.
- Branden C, Tooze J.. Introduction to Protein Structure. New York, NY: Garland Publishing. ISBN: 0-8153-2305-0.
- Irwin H. Segel. Enzyme Kinetics: Behavior and Analysis of Rapid Equilibrium and Steady-State Enzyme Systems (Book 44 izd.). Wiley Classics Library. ISBN 0471303097.
- Robert A. Copeland (2013). Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists (2nd izd.). Wiley-Interscience. ISBN 111848813X.
- Gerhard Michal, Dietmar Schomburg (2012). Biochemical Pathways: An Atlas of Biochemistry and Molecular Biology (2nd izd.). Wiley. ISBN 0470146842.